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AXL (phospho-Y703) polyclonal antibody

货号: BS64021

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS64021

Product Name :AXL (phospho-Y703) polyclonal antibody

Swiss-Prot :P30530

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse (also designated Tyro3, Sky, Brt, Dtk, Etk2 and Tif), Axl (also designated UFO or ARK) and Mer (also designated Nyk or Eyk). Rse is expressed preferentially in the adult brain with lower expression in other tissues. Axl is found at highest levels in heart and skeletal muscle. Mer has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S, have been identified as ligands for the UFO family of receptors.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-AXL (Y703) polyclonal antibody detects endogenous levels of AXL protein only when phosphorylated at Tyr703 (Human) or Tyr697 (Mouse).

BiowMW :~ 98 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Tyrosine-protein kinase receptor UFO; AXL oncogene; UFO; Ark

Immunogen :Synthetic phosphopeptide derived from human AXL around the phosphorylation site of Tyrosine 703.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-AXL (Y703) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:PC12 whole cell lysate

Gas6 attenuates lipopolysaccharide‑induced TNF‑α expression and apoptosis in H9C2 cells through NF‑κB and MAPK inhibition via the Axl/PI3K/Akt pathway

JournalInternational Journal Of Molecular Medicine

ApplicationWB

IF3.098

SpeciesRat

PMID31524235