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ATXN3 polyclonal antibody

货号: BS6285

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6285

Product Name :ATXN3 polyclonal antibody

Swiss-Prot :P54252

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IF

Application_all :WB: 1:500~1:2000 IF: 1:50~1:200

Background :Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination, mediates deubiquitination of monoubiquitinated STUB1/CHIP.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ATXN3 polyclonal antibody detects endogenous levels of ATXN3 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ataxin-3; Machado-Joseph disease protein 1; Spinocerebellar ataxia type 3 protein; ATXN3; ATX3; MJD; MJD1; SCA3

Immunogen :Recombinant full length Human ATXN3.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of ATXN3 polyclonal antibody.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）