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NDRG3 polyclonal antibody

货号: BS62436

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62436

Product Name :NDRG3 polyclonal antibody

Swiss-Prot :Q9UGV2

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC:1:50~1:200

Background :The NDRG (N-Myc downstream-regulated gene) family consisting of NDRG1, NDRG2, NDRG3, and NDRG4 are structurally related proteins with roles in cell proliferation, differentiation, apoptosis, stress responses, and cell migration/metastasis. NDRG1 was originally identified as a protein that was upregulated in N-Myc knockout mice. Proteins in the NDRG family, particularly NDRG1 and NDRG2, have been reported to be down-regulated in various cancer tissues and have been suggested to function as a tumor suppressors. Members of the NDRG family each have distinct expression patterns; NDRG3 is most highly expressed in the testis, prostate, ovary, and brain. NDRG3 has also been shown to be up-regulated by androgen in prostate cell lines and can promote cell growth in those cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity :NDRG3 polyclonal antibody detects endogenous levels of NDRG3 protein.

BiowMW :~ 43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

Immunogen :Synthetic peptide, corresponding to Human NDRG3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of NDRG3 polyclonal antibody at 1:500 dilution LaneA:The brain tissue lysate of Mouse

NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia

JournalONCOLOGY REPORTS

ApplicationWB,IF,IP

IF4.2

SpeciesHuman

PMID37350410