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MMP1 polyclonal antibody

货号: BS6232

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS6232

Product Name :MMP1 polyclonal antibody

Swiss-Prot :P03956

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :55KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MMP1;CLG;CLGN

Immunogen :Recombinant fusion protein of human MMP1(NP_002412.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of SKOV3 cells, using MMP1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 90s.

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SpeciesRat

PMID20447716
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JournalTropical Journal Of Pharmaceutical Research

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SpeciesHuman

PMID
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JournalJournal Of Microbiology Immunology And Infection

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IF3.493

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PMID31734109
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JournalToxicology In Vitro

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IF2.959

SpeciesHuman

PMID
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JournalFebs Letters

ApplicationIHC

IF2.675

SpeciesMouse,Human

PMID30977909