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NCF2 polyclonal antibody

货号: BS6214

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS6214

Product Name :NCF2 polyclonal antibody

Swiss-Prot :P19878

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF/ICC IP

Application_all :WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background :NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NCF2 polyclonal antibody detects endogenous levels of NCF2 protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :67 a neutrophil oxidase factor; Chronic granulomatous disease autosomal 2; NADPH oxidase activator 2; NCF-2; Ncf2; NCF2; Neutrophil cytosol factor 2; Neutrophil NADPH oxidase factor 2; NOXA2; p67-phox; p67phox;

Immunogen :Recombinant full length Human NCF2.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of NCF2 polyclonal antibody in extracts from THP1 cells and mouse spleen tissue.

Immunohistochemistry (IHC) analysis of NCF2 pAb in paraffin-embedded Human Esophageal Cancer tissue.

Immunofluorescence analysis of Hela cells, using NCF2 polyclonal antibody