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CA4 polyclonal antibody

货号: BS61760

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61760

Product Name :CA4 polyclonal antibody

Swiss-Prot :P22748

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Carbonic anhydrase IV (CA IV) is glycosylphosphotidylinositol-anchored to the outer surface of the plasma membrane where it catalyzes hydration-dehydration of CO2/HCO3 - . CA IV is present on the plasma face of microcapillaries and in the choriocapillaris of the human eye. CA IV facilitates renal acidification in the kidney and is responsible for the regulation of interstitial pH (pHo) transients in brain. Impairment in targetting leads to disruption of HCO3 - secretion and associates with malfunction in cystic fibrosis cells. Carbonic anhydrases are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Carbonic anhydrases show extensive diversity in tissue distribution and in their subcellular localization.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CA4 polyclonal antibody detects endogenous levels of CA4 protein.

BiowMW :~ 35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Carbonic anhydrase 4; Carbonate dehydratase IV; Carbonic anhydrase IV; CA-IV; CA4

Immunogen :Synthetic peptide, corresponding to amino acids 120-170 of Human CA4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CA4 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:HepG2 whole cell lysate(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:AML-12 whole cell lysate(40ug) Lane5:PC12 whole cell lysate(40ug)