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B4GALT5 polyclonal antibody

货号: BS61542

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61542

Product Name :B4GALT5 polyclonal antibody

Swiss-Prot :O43286

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed to B4GALT5. In the literature it is also referred to as beta4GalT2.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :B4GALT5 polyclonal antibody detects endogenous levels of B4GALT5 protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Beta-1,4-galactosyltransferase 5; Beta-1,4-GalTase 5; Beta4Gal-T5; b4Gal-T5; Beta-1,4-GalT II;

Immunogen :Synthetic peptide, corresponding to amino acids 321-365 of HumanV.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of B4GALT5 polyclonal antibody at 1:500 dilution Lane1:786-O whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:The kidney tissue lysate of Mouse(40ug) Lane4:The kidney tissue lysate of Rat(40ug)

B4GALT5 high expression associated with poor prognosis of hepatocellular carcinoma

JournalBMC CANCER

ApplicationWB

IF4.43

SpeciesHuman

PMID35410157