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CD79B polyclonal antibody

货号: BS60825

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60825

Product Name :CD79B polyclonal antibody

Swiss-Prot :P40259

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :CD79 (also designated Ig α/Ig β) is a heterodimer composed of α chains, designated CD79A or MB-1, and β chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif,which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 99% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -24°C long term. Avoid freeze-thaw cycles.

Specificity :CD79B polyclonal antibody detects endogenous levels of CD79B protein.

BiowMW :~ 39 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :B cell receptor signaling,

Alternative Name :B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD79b; CD79B; B29; IGB

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD79b. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of CD79b expression in mouse heart (A), mouse spleen (B) whole cell lysates.