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ARHGAP30 polyclonal antibody

货号: BS60757

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60757

Product Name :ARHGAP30 polyclonal antibody

Swiss-Prot :Q7Z6I6

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. ARHGAP30 (Rho GTPase activating protein 30), also known as Rho-type GTPase-activating protein 30, is a 1,101 amino acid protein that contains one Rho-GAP domain and exists as four alternatively spliced isoforms. Conserved in chimpanzee, dog, cow, mouse and rat, ARHGAP30 is among the most neurite-enriched GAPs, which also includes ARHGAP21, FNBP2 and Bcr). One of four single-nucleotide polymorphisms (SNPs) at the USF-1 gene locus, rs2774279, which is located in the promoter area of the USF-1 gene, which is in turn located within its flanking gene ARHGAP30, is linked to low-density lipoprotein cholesterol levels, incident type 2 diabetes mellitus and increased cardiovascular risk.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ARHGAP30 polyclonal antibody detects endogenous levels of ARHGAP30 protein.

BiowMW :~ 119 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Rho GTPase-activating protein 30; Rho-type GTPase-activating protein 30; ARHGAP30

Immunogen :A synthetic peptide corresponding to residues in Human ARHGAP30

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ARHGAP30 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate