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Integrin alpha 4 (ITGA4/CD49d) polyclonal antibody

货号: BS6061

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6061

Product Name :Integrin alpha 4 (ITGA4/CD49d) polyclonal antibody

Swiss-Prot :P13612

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:100

Background :The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :70KDa/140KDa/150KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ITGA4;CD49D;IA4

Immunogen :Recombinant fusion protein of human Integrin alpha 4 (ITGA4/CD49d)(NP_000876.3).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Jurkat, using Integrinalpha4 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 180s.

Cytological study on the regulation of lymphocyte homing in the chicken spleen during LPS stimulation

JournalOncotarget

ApplicationWB

IF0

SpeciesChicken

PMID28061467