Product Name :MSH2 polyclonal antibody
Reactivity :Human, Mouse, Rat
Applications :WB, IF/ICC, IP
Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200|IP,1:20 - 1:50
Background :This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Polyclonal Antibodies
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MSH2;COCA1;FCC1;HNPCC;HNPCC1;LCFS2
Immunogen :Recombinant fusion protein of human MSH2(NP_000242.1).
Modification :Unmodification
