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ATP6V1G3 polyclonal antibody

货号: BS60498

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60498

Product Name :ATP6V1G3 polyclonal antibody

Swiss-Prot :Q96LB4

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (A–H) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. In yeast, the V-ATPase G subunit is a soluble subunit that shares homology with the F-ATPase G subunit and may be part of a connection stalk between V1 and V0. The G2 isoform of the G subunit associates with the pore-forming a1C-subunit of L-type calcium channel and aids in proper membrane targeting of the calcium channel. The genes encoding the G1 and G2 V-ATPase subunits map to chromosomes 9q33.1 and 6p21.3, respectively.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ATP6V1G3 polyclonal antibody detects endogenous levels of ATP6V1G3 protein.

BiowMW :~ 14 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :V-type proton ATPase subunit G 3; V-ATPase subunit G 3; V-ATPase 13 kDa subunit 3; Vacuolar proton pump subunit G 3; ATP6V1G3; ATP6G3

Immunogen :A synthetic peptide corresponding to residues in Human ATP6V1G3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ATP6V1G3 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:PC12 whole cell lysate