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IL17A polyclonal antibody

货号: BS6041

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6041

Product Name :IL17A polyclonal antibody

Swiss-Prot :Q16552

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB,1:500 - 1:2000|IF,1:50 - 1:200

Background :The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :18-25KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IL17A;CTLA-8;CTLA8;IL-17;IL-17A;IL17

Immunogen :Recombinant fusion protein of human IL17A(NP_002181.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of various lysates, using IL17A antibody at 1:500 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 30s.

Aberrant Activation of the STING-TBK1 Pathway in γδ T Cells Regulates Immune Responses in Oral Lichen Planus

JournalBiomedicines

ApplicationWB

IF4.757

SpeciesHuman

PMID36979934