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CD8B polyclonal antibody

货号: BS60358

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60358

Product Name :CD8B polyclonal antibody

Swiss-Prot :P10966

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The T cell receptor (TCR) is a heterodimercomposed of either α and β or γ and δ chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficientsignal transduction through the TCR. The TCR is expressed on T helper and T cytotoxiccellsthatcan be distinguished bytheir expression of CD4 and CD8. T helpercells express CD4 proteins and T cytotoxiccells display CD8. CD8 (also designated Leu 2 or T8), a cellsurface glycoprotein, is a two chain complex(αα or αβ) receptor that bindsclassI MHC molecules presented bythe antigen-presenting cell (APC). A primaryfunction of CD8 is to facilitate antigen recognition bythe TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cellsmay be tomaintain lowlevels of HIV expression.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD8B polyclonal antibody detects endogenous levels of CD8B protein.

BiowMW :~ 26 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :T-cell surface glycoprotein CD8 beta chain; CD_antigen=CD8b; CD8B ; CD8B1

Immunogen :A synthetic peptide corresponding to residues in Human CD8B.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD8B polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate