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IFN-α polyclonal antibody（KU）

货号: BS60294

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60294

Product Name :IFN-α polyclonal antibody（KU）

Swiss-Prot :P01562

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:1000~1:2000

Background :Interferons (IFNs) appear both locally and systematically early after viral infection and participate in limiting the spread of infection. They also affect cell differentiation, growth, surface antigen expression, and immunoregulation. There are three naturally occurring interferons: α, β, and γ. IFN-α is derived from lymphoblastic tissue and has a number of therapeutic applications in the treatment of various human cancers and diseases of viral origin. Recombinant IFN-α from both natural and synthetic genes binds to a common cell surface receptor and induces antiviral activity in a variety of cell lines. When binding to discrete cell surface receptors on target cells, IFN-α induces rapid changes in Jak/Stat phosphorylation, which initiates the Jak/Stat signaling pathway. IFN-α signaling also involves production of DAG without an increased intracellular free calcium concentration and the subsequent activation of calcium-independent isoforms of PKC (β and ε). All IFN-α signaling pathways lead to final alterations of gene expression, which mediate their pleiotropic biologic activities.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IFN-α polyclonal antibody detects endogenous levels of IFN-α protein.

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interferon alpha-1/13; IFN-alpha-1/13; Interferon alpha-D (LeIF D); IFNA1; IFNA13

Immunogen :Synthetic peptide, corresponding to Human IFN-α.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of IFN-α polyclonal antibody at 1:1000 dilution Lane1:IFN-α recombinant protein(0.2ug)

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）