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CABYR polyclonal antibody

货号: BS60128

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60128

Product Name :CABYR polyclonal antibody

Swiss-Prot :O75952

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Spermatozoa gain fertilization capacitation and hyperactivation after residing in the uterus or oviduct. Calcium, cAMP and protein tyrosine phosphorylation are necessary for the molecular mechanisms that allow for this transformation. CABYR (Calcium-binding tyrosine phosphorylation-regulated protein), also known as Fibrousheathin-2 or Cancer/testis antigen 88, is a 493 amino acid protein that is expressed in sperm flagella and exhibits increased tyrosine phosphorylation during capacitation. There are six named isoforms of CABYR that are produced as a result of alternative slicing events. Specifically, isoform 1 is expressed in the testis, while isoform 3 and isoform 5 are expressed in pancreas, brain and various brain tumors. Isoforms 1, 2 and 6 most likely bind calcium, whereas isoforms 3, 4 and 5 probably do not bind calcium.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CABYR polyclonal antibody detects endogenous levels of CABYR protein.

BiowMW :~ 30, 53 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Calcium-binding tyrosine phosphorylation-regulated protein; Calcium-binding protein 86; Cancer/testis antigen 88; CT88; Fibrousheathin II; Fibrousheathin-2; FSP-2; Testis-specific calcium-binding protein CBP86; CBP86; FSP2

Immunogen :A synthetic peptide corresponding to residues in Human CABYR.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CABYR polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate