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ARHGDIG polyclonal antibody

货号: BS5899

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5899

Product Name :ARHGDIG polyclonal antibody

Swiss-Prot :Q99819

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB ICC

Application_all :WB: 1:500~1:1000 ICC: 1:50~1:200

Background :The Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to proliferation, cytoskeletal organization and secretion. The counter-conversion of the active GTPbound form of these proteins to their inactive GDP-bound form is influenced by two types of regulatory proteins: those that alter the intrinsic GTPase activity of the GTP-binding proteins and those that alter the rate of GDP/GTP exchange. Guanine nucleotide-releasing factors (GRFs) increase the GDP dissociation rate, while GDP-dissociation inhibitors (GDIs) decrease the dissociation rate. The Rho GDI subfamily is composed of Rho GDIα, Ly-GDI (also known as Rho GDIβ and previously known as GDI/D4) and Rho GDIγ. The Rho GDI proteins interact with and have varying affinities for several Ras-like GTP binding proteins, including Rho A, Rho B, Rac and Cdc42. Ly-GDI is expressed only in hematopoietic cells, predominantly in B and T lymphocyte cell lines.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ARHGDIG polyclonal antibody detects endogenous levels of ARHGDIG protein.

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Rho GDP-dissociation inhibitor 3; Rho GDI 3; Rho-GDI gamma; Rho GDIγ; Rho-GDIγ

Immunogen :Synthetic peptide, corresponding to amino acids 176-221 of Human ARHGDIG.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ARHGDIG polyclonal antibody at 1:500 dilution Lane1:Jurkat cell lysate Lane2:Hela cell lysate Lane3:Raw264.7 cell lysate