Product Name :Brn-3c polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:500~1:1000
Background :Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Brn-3c polyclonal antibody detects endogenous levels of Brn-3c protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :POU domain, class 4, transcription factor 3; Brain-specific homeobox/POU domain protein 3C; Brain-3C; Brn-3C; POU4F3; BRN3C
Immunogen :Synthetic peptide, corresponding to amino acids 263-308 of Human Brn-3c.
Modification :Unmodification
