Product Name :ARG1 polyclonal antibody
Application_all :WB: 1:500~1:1000
Background :Arginase I (also designated liver-type arginase), which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea. The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :ARG1 polyclonal antibody detects endogenous levels of ARG1 protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Immune checkpoint signaling in the Tumor Microenvironment,Tumor-Infiltrating Immune Cell Marker Guide,
Alternative Name :Arginase1; Arginase 1; Arginase-1; Liver-type arginase; Type I arginase; ARG-1
Immunogen :Synthetic peptide, corresponding to amino acids 105-150 of Human ARG1.
Modification :Unmodification
