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TRIM56 Recombinant Rabbit mAb (KU)

货号: BS49542

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS49542

Product Name :TRIM56 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q9BRZ2

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF,FC

Application_all :WB:1:10000<br />IHC: 1:200-1:1000<br />ICC/IF: 1:50-1:100<br />FC: 1:20

Background :E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity (PubMed:21289118). In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets TMEM173/STING to 'Lys-63'-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta (By similarity). Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling. Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXCL10, OASL and CCL5/RANTES. Promotes establishment of an antiviral state by TLR3 ligand and TLR3-mediated chemokine induction following infection by hepatitis C virus (PubMed:22948160).

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :82 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RNF109

Immunogen :A synthetic peptide of human TRIM56

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of TRIM56 in Hela cell lysates using TRIM56 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）