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Carma 1/CARD11 Recombinant Rabbit mAb (KU)

货号: BS48987

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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详细信息检测数据实验指南文献

No. :BS48987

Product Name :Carma 1/CARD11 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q9BXL7

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,ICC/IF

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200

Background :The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 15 kDa; Observed MW: 15 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :H3 histone; family 3A; H3 histone; family 3B (H3.3B); H3.3A; H3.3B; H33; H3F3; H3F3A; H3F3B; Histone H3.3

Immunogen :Human Phospho-Histone H3(Ser10) synthetic peptide conjugated to KLH.

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Histone H3 in HeLa lysates, untreated or 1mM hydroxyurea treated for 5 hours, using Phospho-Histone H3 antibody.

免疫沉淀（IP）