Product Name :PHF1 Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB,IHC,ICC/IF,FC
Background :This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]