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Nuclear Factor Erythroid Derived 2 Recombinant Rabbit mAb (KU)

货号: BS48145

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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No. :BS48145

Product Name :Nuclear Factor Erythroid Derived 2 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q16621

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,FC

Background :Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.