Product Name :Dnmt3a Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB,ICC/IF,FC
Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Background :CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification&Purity :Affinity Purified
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BiowMW :Calculated MW: 45 kDa; Observed MW: 45 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PGKA; MIG10; HEL-S-68p
Immunogen :A synthesized peptide derived from human PGK1