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GSDMD Recombinant Rabbit mAb (KU)

货号: BS48109
价格 1200
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS48109
Product Name :GSDMD Recombinant Rabbit mAb (KU)
Swiss-Prot :Q9D8T2
Host :Rabbit
Reactivity :Mouse
Applications :WB,IP
Application_all :WB: 1:1000<br />IP: 1:20
Background :Gasdermin-D, N-terminal: Promotes pyroptosis in response to microbial infection and danger signals. Produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4 in response to canonical, as well as non-canonical (such as cytosolic LPS) inflammasome activators (PubMed:26611636, PubMed:26375259, PubMed:26375003, PubMed:27418190, PubMed:27385778, PubMed:27383986). After cleavage, moves to the plasma membrane where it strongly binds to membrane inner leaflet lipids, including monophosphorylated phosphatidylinositols, such as phosphatidylinositol 4-phosphate, bisphosphorylated phosphatidylinositols, such as phosphatidylinositol (4,5)-bisphosphate, as well as phosphatidylinositol (3,4,5)-trisphosphate, and more weakly to phosphatidic acid and phosphatidylserine.
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :IgG
BiowMW :53 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DF5L; M2-4; Dfna5l; Gsdmdc1; AW558049; 1810036L03Rik
Immunogen :A synthetic peptide of mouse GSDMD
Conjugate :Unconjugated
Modification :Unmodification

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com