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MUC16 Recombinant Rabbit mAb (KU)

货号: BS47639

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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详细信息检测数据实验指南文献

No. :BS47639

Product Name :MUC16 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q8WXI7

Host :Rabbit

Reactivity :Human

Applications :WB,IHC

Application_all :WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Background :This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. [provided by RefSeq, May 2017]

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Catenin-α1 polyclonal antibody detects endogenous levels of Catenin-α1 protein.

BiowMW :~ 115kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13; CTNNA1; Catenin-α1; Catenin α1; αE-catenin; Catenin alpha-2; Alpha N-catenin; Alpha-catenin-related protein; CTNNA2; CAPR; Catenin-α2; Catenin α2; αN-catenin;

Immunogen :Recombinant full length Human Catenin-α1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Catenin-α1 polyclonal antibody