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Vav proteins Recombinant Rabbit mAb (KU)

货号: BS47618

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47618

Product Name :Vav proteins Recombinant Rabbit mAb (KU)

Swiss-Prot :P15498

Host :Rabbit

Reactivity :Human

Applications :WB,ICC/IF,FC,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background :This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 44 kDa; Observed MW: 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :APOL1; APOL; Apolipoprotein L1; Apolipoprotein L; Apo-L; ApoL; Apolipoprotein L-I; ApoL-I

Immunogen :A synthetic peptide of human Apolipoprotein L 1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Apolipoprotein L1/APOL1 in Human serum lysates using ApoL1 antibody.

免疫沉淀（IP）