Product Name :NFkB p100 Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB,ICC/IF,FC,IP
Application_all :WB: 1:1000<br />ICC/IF: 1:100<br />FC: 1:20<br />IP: 1:20
Background :This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
Immunogen :Recombinant protein of human NFkB p100
Modification :Unmodification
