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C4b Recombinant Rabbit mAb (KU)

货号: BS47413

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47413

Product Name :C4b Recombinant Rabbit mAb (KU)

Swiss-Prot :P0C0L5

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:1000<br />IHC: 1:100<br />ICC/IF: 1:100

Background :This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. This GeneID and its associated RefSeq record represent a second copy of C4B found on ALT_REF_LOCI_7. [provided by RefSeq, Jul 2011]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :193 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CO4; CPAMD3

Immunogen :Recombinant protein of human C4b

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts from HepG2 cells using db14257 at 1:1000.

免疫沉淀（IP）

免疫组织化学（IHC）