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RAPGEF5 Recombinant Rabbit mAb (KU)

货号: BS47367

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47367

Product Name :RAPGEF5 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q92565, Q8C0Q9, P83900

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC

Application_all :WB: 1:1000<br />IHC: 1:200<br />ICC/IF: 1:100<br />FC: 1:20

Background :Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :68-75 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GFR; REPAC; MR-GEF

Immunogen :A synthetic peptide of human RAPGEF5

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts from HeLa cells using db11521 at 1:1000.

免疫沉淀（IP）

免疫组织化学（IHC）