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MEK3 Recombinant Rabbit mAb (KU)

货号: BS47303

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47303

Product Name :MEK3 Recombinant Rabbit mAb (KU)

Swiss-Prot :P46734

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC, IP

Application_all :WB: 1:1000<br />IHC: 1:50<br />ICC/IF: 1:50<br />FC: 1:100<br />IP: 1:20

Background :The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :38-40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2

Immunogen :Recombinant protein of human MEK3

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of MEK3 in C6,3T3,Hela cell lysates using MEK3 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）