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MCM6 Recombinant Rabbit mAb (KU)

货号: BS47302

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47302

Product Name :MCM6 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q14566

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:1000<br />IHC: 1:500<br />ICC/IF: 1:50<br />FC: 1:20<br />IP: 1:20

Background :The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood. [provided by RefSeq, May 2012]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :93 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Mis5; P105MCM; MCG40308

Immunogen :Recombinant protein of human MCM6

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of MCM6 in Jurkat cell lysates using MCM6 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）