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ASK1 Recombinant Rabbit mAb (KU)

货号: BS47301

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :BS47301

Product Name :ASK1 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q99683

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IHC, ICC/IF, FC

Application_all :WB: 1:1000<br />IHC: 1:50<br />ICC/IF: 1:20-1:50<br />FC: 1:20

Background :Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :155 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ASK1; MEKK5; MAPKKK5

Immunogen :A synthetic peptide of human ASK1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of ASK1 in Hela cell lysates using ASK1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）