Product Name :KIF5B Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB,IHC,ICC/IF,IP
Background :Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726).