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FADD Recombinant Rabbit mAb (KU)

货号: BS47233

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47233

Product Name :FADD Recombinant Rabbit mAb (KU)

Swiss-Prot :Q13158

Host :Rabbit

Reactivity :Human

Applications :WB, IHC, ICC/IF, FC, IP

Application_all :WB: 1:1000-1:5000<br />IHC: 1:20-1:100<br />ICC/IF: 1:20-1:50<br />FC: 1:20<br />IP: 1:20-1:50

Background :The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GIG3; MORT1

Immunogen :A synthetic peptide of human FADD

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of FADD in Rat Brain,3T3 cell lysates using FADD antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）