Product Name :Integrin Linked ILK Recombinant Rabbit mAb (KU)
Reactivity :Human, Mouse, Rat
Applications :WB, ICC/IF, FC, IP
Background :This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
