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FEN1 Recombinant Rabbit mAb (KU)

货号: BS46637

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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详细信息检测数据实验指南文献

No. :BS46637

Product Name :FEN1 Recombinant Rabbit mAb (KU)

Swiss-Prot :P39748

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC

Application_all :WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Background :The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008]

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Catenin-α1 polyclonal antibody detects endogenous levels of Catenin-α1 protein.

BiowMW :~ 115kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13; CTNNA1; Catenin-α1; Catenin α1; αE-catenin; Catenin alpha-2; Alpha N-catenin; Alpha-catenin-related protein; CTNNA2; CAPR; Catenin-α2; Catenin α2; αN-catenin;

Immunogen :Recombinant full length Human Catenin-α1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Catenin-α1 polyclonal antibody