Product Name :Caspase-2 Recombinant Rabbit mAb (KU)
Swiss-Prot :P42575, P29594, P55215
Reactivity :Human, Mouse, Rat
Applications :WB, IHC, ICC/IF, FC
Background :This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
