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CD31 Recombinant Rabbit mAb (KU)

货号: BS45621

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45621

Product Name :CD31 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q08481

Host :Rabbit

Reactivity :Mouse, Rat

Applications :WB,ICC/IF

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200

Background :Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 15 kDa; Observed MW: 15 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :H3 histone; family 3A; H3 histone; family 3B (H3.3B); H3.3A; H3.3B; H33; H3F3; H3F3A; H3F3B; Histone H3.3

Immunogen :Human Phospho-Histone H3(Ser10) synthetic peptide conjugated to KLH.

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Histone H3 in HeLa lysates, untreated or 1mM hydroxyurea treated for 5 hours, using Phospho-Histone H3 antibody.

免疫沉淀（IP）