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beta Catenin Recombinant Rabbit mAb (KU)

货号: BS45552

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45552

Product Name :beta Catenin Recombinant Rabbit mAb (KU)

Swiss-Prot :P35222

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,FC

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100

Background :The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 45 kDa; Observed MW: 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PGKA; MIG10; HEL-S-68p

Immunogen :A synthesized peptide derived from human PGK1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PGK1 in HepG2 lysates; mouse kidney lysates using PGK1 antibody.

Western blot analysis of PGK1 in SKOV-3, Jurkat, U251, PC-3 and Hela lysates using PGK1 antibody.