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LEF-1 (F38) polyclonal antibody（KU）

货号: BS3974

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3974

Product Name :LEF-1 (F38) polyclonal antibody（KU）

Swiss-Prot :Q9UJU2

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB IF

Application_all :WB: 1:1000~1:2000 IF: 1:100~1:500

Background :Transcription factor that binds DNA in a sequence-specific manner.Participates in the Wnt signaling pathway (By similarity).Activates transcription of target genes in the presence of CTNNB1 and EP300 (By similarity).PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1.Regulates T-cell receptor alpha enhancer function.Required for IL17A expressing gamma-delta T-cell maturation and development, via binding to regulator loci of BLK to modulate expression (By similarity).May play a role in hair cell differentiation and follicle morphogenesis (By similarity).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LEF-1 polyclonal antibody detects endogenous levels of LEF-1 protein.

BiowMW :~ 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Adherens Junction signaling,Wntβ catenin signaling,

Alternative Name :Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha

Immunogen :Synthetic peptide, corresponding to Human LEF-1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of LEF-1 polyclonal antibody at 1:1000 dilution Lane1:The brain tissue lysate of Mouse(30ug) Lane2:The brain tissue lysate of Rat(30ug) Lane3:HuT78 whole cell lysate(30ug) Lane4:myla2059 whole cell lysate(30ug)