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C1S (K583) polyclonal antibody（KU）

货号: BS3839

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3839

Product Name :C1S (K583) polyclonal antibody（KU）

Swiss-Prot :P09871

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :C1s proenzyme is a glycoprotein produced primarily by hepatocytes but also by other cells. The proenzyme is produced as a single chain polypeptide of 688 aa. Upon activation the peptide is cleaved between R437 and I438 giving the activated enzyme consisting of two disulfide-linked chains, A chain (52.2 kDa) and B chain (27.7 kDa). The Ca dependent catalytic subunit of the C1 complex (C1q, C1r, C1s) comprises of two C1s and two C1r molecules and this serine protease tetramer is responsible for the initial steps in the classical complement pathway, cleavage of C4 and C2.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :C1s (K583) polyclonal antibody detects endogenous levels of C1s protein.

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C1 esterase; Complement C1s subcomponent; Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain; Complement component 1 s subcomponent

Immunogen :Synthetic peptide, corresponding to amino acids 551-600 of Human C1S.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of C1s (K583) pAb at 1:500 dilution Lane1:AML-12 whole cell lysate(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:HepG2 whole cell lysate(40ug) Lane4:SK-OVCAR3 whole cell lysate(40ug)