Product Name :CaMKIIβ/γ/δ (S280) polyclonal antibody
Swiss-Prot :Q13555/Q13554/Q13557
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:500~1:1000
IHC: 1:50~1:200
Background :The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated α, β, γ and δ, which may or may not be coexpressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :CaMKIIβ/γ/δ (S280) polyclonal antibody detects endogenous levels of CaMKIIβ/CaMKIIγ/CaMKIIδ protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Phospholipase Signaling,Phospholipase Signaling,Contribution of Soluble Factors to EMT,G Protein-coupled Receptors Signaling to MAPK Erk,G Protein-coupled Receptors Signaling to MAPK Erk,Mitochondrial Control of Apoptosis,ErbB HER Signaling,
Alternative Name :Calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2B; CAM2; CAMK2; CAMKB; Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II subunit gamma; CaMK-II subunit gamma; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II subunit delta; CaMK-II subunit delta; CAMK2D; CAMKD
Immunogen :Synthetic peptide, corresponding to amino acids 248-299of Human CaMKIIβ.
Modification :Unmodification
