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Calpain 2 (K354) polyclonal antibody（KU）

货号: BS3696

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3696

Product Name :Calpain 2 (K354) polyclonal antibody（KU）

Swiss-Prot :P17655

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Mu Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Calpain 2 (K354) polyclonal antibody detects endogenous levels of Calpain-2 catalytic subunit protein.

BiowMW :~ 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Calpain-2 catalytic subunit; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpain; CANPL2; CAPN2

Immunogen :Synthetic peptide, corresponding to amino acids 320-370 of Human Calpain 2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Calpain 2 (K354) pAb at 1:500 dilution Lane1:Beas-2B whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:PC3 whole cell lysate(40ug) Lane4:The Kidney tissue lysate of Mouse(40ug) Lane5:The Kidney tissue lysate of Rat(40ug)

Triptolide protects against TGF‑β1‑induced pulmonary fibrosis by regulating FAK/calpain signaling

JournalExperimental and Therapeutic Medicine

ApplicationWB

IF1.448

SpeciesHuman

PMID31777561