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BNIP-3 (E96) polyclonal antibody

货号: BS3545

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS3545

Product Name :BNIP-3 (E96) polyclonal antibody

Swiss-Prot :Q12983

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC: 1:50~1:200

Background :BNIP3, formerly NIP3 (nineteen kDa interacting protein-3), is a pro-apoptotic, mitochondrial protein classified in the Bcl 2 family based on limited sequence homology to the Bcl 2 homology 3 (BH3) domain (amino acids 110-118) and C-terminal TM domain. BNIP3 expressed in yeast and mammalian cells interacts with survival promoting proteins Bcl 2, Bcl XL, CED9 and the adenovirus E1B 19K protein. BNIP3 represents a subfamily of Bcl 2 related proteins, which functions without a typical BH3 domain to regulate apoptosis from both mitochondrial and nonmitochondrial sites by selective Bcl 2/Bcl XL interactions.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :BNIP-3 (E96) polyclonal antibody detects endogenous levels of BNIP-3 protein.

BiowMW :~ 22, 30, 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Autophagy Signaling,

Alternative Name :BNIP3; NIP3

Immunogen :Synthetic peptide, corresponding to amino acids 70-120 of Human BNIP-3.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of BNIP-3 (E96) pAb in paraffin-embedded human brain tissue.

免疫沉淀（IP）

免疫组织化学（IHC）