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CD63 (K156) polyclonal antibody（KU）

货号: BS3474

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3474

Product Name :CD63 (K156) polyclonal antibody（KU）

Swiss-Prot :P08962

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :CD63 (also known as LAMP-3, Melanoma-associated antigen ME491, TSPAN30, MLA1 and OMA81H) is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD63 (K156) polyclonal antibody detects endogenous levels of CD63 protein.

BiowMW :~ 25-60 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor-Infiltrating Immune Cell Marker Guide,Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :CD63 antigen; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD63; MLA1; TSPAN30

Immunogen :Synthetic peptide, corresponding to amino acids 111-160 of Human CD63.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CD63 (K156) pAb at 1:1000 dilution Lane1:C6 whole cell lysate(30ug) Lane2:SP2/0 whole cell lysate(30ug) Lane3:K562 whole cell lysate(30ug) Lane4:A549 whole cell lysate(30ug)

Immunohistochemistry (IHC) analyzes of CD63 (K156) pAb in paraffin-embedded human lung carcinoma tissue.

Hepatoprotective effect of exosomes from human-induced pluripotent stem cell–derived mesenchymal stromal cells against hepatic ischemia-reperfusion injury in rats

JournalCytotherapy

ApplicationWB

IF4.218

SpeciesHuman

PMID27592404
Placenta‑associated serum exosomal miR‑155 derived from patients with preeclampsia inhibits eNOS expression in human umbilical vein endothelial cells

JournalInternational Journal Of Molecular Medicine

ApplicationWB

IF4.101

SpeciesHuman

PMID29328396
Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7

JournalInternational Journal Of Molecular Medicine

ApplicationWB

IF3.098

SpeciesHuman

PMID29484378