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TGF beta Receptor I (TGFBR1) polyclonal antibody（KU）

货号: BS3257

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3257

Product Name :TGF beta Receptor I (TGFBR1) polyclonal antibody（KU）

Swiss-Prot :P36897

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :56KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TGFBR1;AAT5;ACVRLK4;ALK-5;ALK5;ESS1;LDS1;LDS1A;LDS2A;MSSE;SKR4;TGFR-1;tbetaR-I;TBRI;TBR-i

Immunogen :Recombinant fusion protein of human TGF beta Receptor I (TGF beta Receptor I (TGFBR1))(NP_001124388.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of 293T cells, using TGF beta Receptor I ) antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 180s.

Western blot analysis of extracts of various cell lines, using TGF beta Receptor I ) antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit .
Exposure time: 180s.

Dental and periodontal phenotypes of Dlx2 overexpression in mice

JournalMolecular Medicine Reports

ApplicationIHC

IF1.851

SpeciesMouse

PMID28447749
Alteration of TGF-β-ALK-Smad signaling in hyperoxia-induced bronchopulmonary dysplasia model of newborn rats

JournalExperimental Lung Research

ApplicationIHC

IF1.702

SpeciesRat

PMID27618520
Research on function and mechanisms of a novel small molecule WG449E for hypertrophic scar

JournalJournal Of The European Academy Of Dermatology And Venereology

ApplicationWB

IF5.248

SpeciesHuman

PMID31650631