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Calponin 2 (D156) polyclonal antibody（KU）

货号: BS3097

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3097

Product Name :Calponin 2 (D156) polyclonal antibody（KU）

Swiss-Prot :Q99439

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Calponin, a 34 kDa protein, regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an actin- and tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-actin and inhibition of the actin-activated MgATPase activity of phosphorylated myosin.Both properties are lost following phosphorylation (primarily at serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin), and Calponin 3 (acidic Calponin) are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Calponin 2 (D156) polyclonal antibody detects endogenous levels of Calponin 2 protein.

BiowMW :~ 33 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Calponin-2; Calponin H2, smooth muscle; Neutral calponin; CNN2

Immunogen :Synthetic peptide, corresponding to amino acids 122-170 of Human Calponin 2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Calponin 2 (D156) pAb at 1:500 dilution Lane1:AML-12 whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(20ug) Lane3:L02 whole cell lysate(40ug) Lane4:HepG2 whole cell lysate(40ug) Lane5:Hela whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Calponin 2 (D156) pAb in paraffin-embedded human brain tissue.