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Calmodulin (K75) polyclonal antibody（KU）

货号: BS2989

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2989

Product Name :Calmodulin (K75) polyclonal antibody（KU）

Swiss-Prot :P62158

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. CaM directly modulates the activity of protein kinases and phosphatases, ion channels and nitric oxide synthetases. It is generally involved in such diverse processes as cell proliferation, endocytosis, cellular adhesion, protein turn over and smooth muscle contraction. CaM (calmodulin) is an acidic protein, 148 amino acids in length, with four helix-loop-helix calcium binding domains.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Calmodulin (K75) polyclonal antibody detects endogenous levels of Calmodulin protein

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Calmodulin; CaM; CALM1; CALM; CAM; CAM1; CALM2; CAM2; CAMB; CALM3; CALML2; CAM3; CAMC; CAMIII

Immunogen :Synthetic peptide, corresponding to amino acids 50-100 of Human Calmodulin.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Calmodulin (K75) pAb at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:PC3 whole cell lysate(40ug) Lane3:C6 whole cell lysate(40ug) Lane4:BV2 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Calmodulin (K75) pAb in paraffin-embedded human brain and breast carcinoma tissue.

ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca2+/calmodulin Signaling Pathway and Ca2+-associated eNOS Activation in Endothelial Cells

JournalInternational Journal of Biological Sciences

ApplicationIP

IF4.858

SpeciesHuman

PMID29104511