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Cadherin-8 (A519) polyclonal antibody（KU）

货号: BS2578

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2578

Product Name :Cadherin-8 (A519) polyclonal antibody（KU）

Swiss-Prot :P55286

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. Cadherin-8 expression has been seen in mouse thymus tissue as well as in specific subdivisions of the developing central nervous system. It plays a potential role in brain morphology.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cadherin-8 (A519) polyclonal antibody detects endogenous levels of Cadherin-8 protein.

BiowMW :~ 88 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cadherin 8; CADH8; Cadherin8

Immunogen :Synthetic peptide, corresponding to amino acids 500-550 of Human Cadherin-8.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Cadherin-8 (A519) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat liver tissue lysate

Immunohistochemistry (IHC) analyzes of Cadherin-8 (A519) pAb in paraffin-embedded human brain tissue.